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In PDAC, CAFs expressing Meflin were associated with a better response to chemotherapy, and inducing Meflin expression in CAFs could enhance sensitivity of PDAC tumours to gemcitabine [247]

There was a discrepancy between the previous results and the results of a meta-analysis, which demonstrated no significant effect of L-carnitine on all-cause mortality or major cardiac events, including heart failure, unstable angina, and myocardial reinfarction

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